Gut - Health Rising

Takeaways From the Big Long COVID Clinical Trials

by Cort Johnson | Apr 21, 2026 | Amytriptyline, Antivirals, CoQ10, COVID-19, Homepage, Inflammation, Ivabradine, Klimas, Lipids, long COVID, Mast cell activation syndrome, Microbiome, Orthostatic intolerance, Paxlovid, POTS, Treatment

Only 10 major long COVID clinical trials have been published thus far but that's enough to come away with some interesting takeaways. They include treatments that prevent long COVID don't necessarily treat it, broader based treatments are probably best, manipulating the gut can help with fatigue (but only so much), and an as yet unassessed class of drugs may be helpful.

Are All Roads Leading to the Immune System and the Blood in ME/CFS?

by Cort Johnson | Apr 14, 2026 | Autonomic Nervous System, Brain, Brainstem, Cardiovascular, Cerebral Spinal Fluid, Clotting, Complement, Connective Tissues, Endothelial Cells, Energy Production, Gut, Homepage, Immune, Mast cell activation syndrome, Metabolism, Microbiome, Neuroinflammation, Neuroinflammation, Neutrophils, POTS, Proteomics, T-cells

What happens when you throw ten or so very different ME/CFS studies together? You get some core themes popping out. Check out the blog and see what they are.

The GLP-1 Agonist Boom in ME/CFS, FM and Long COVID: Insights, Using it, Trials Underway

by Cort Johnson | Nov 3, 2025 | COVID-19, Dempsey, Epstein-Barr Virus, GLP-1, Gut, Homepage, Immune, Inflammation, Kaufman, Mast cell activation syndrome, Mast cell activation syndrome, Neuroinflammation, Pathogens, POTS, RECOVER Initiative, Severe ME/CFS, Treatment

Complex, chronic illness experts discuss what GLP-1 agonists can and can't do in diseases like ME/CFS, long COVID, and POTS. Plus new long COVID trials.

Gut Reactions: BioMapAI Points to Multiple Dysregulated Systems in ME/CFS

by Cort Johnson | Sep 12, 2025 | B-cells, Connective Tissues, Cytokines, DeCodeME, Energy Production, Genetics, Gut, Homepage, Immune, Inflammation, Leaky gut, Lipids, Liver, Liver and urea cycle, ME/CFS, Metabolism, Microbiome, Oxidative Stress, Research, Serotonin, T-cells, Tryptophan

BioMapAI study suggests the gut problems in ME/CFS are driving other system malfunctions and symptoms.

“Screaming Immune Activation”: Major Lipkin Study Finds ME/CFS Systems Folding Under the Stress

by Cort Johnson | Sep 5, 2025 | Complement, Connective Tissues, Cytokines, Energy Production, Exercise, Gut, Homepage, Hormones, Immune, Inflammation, Leaky gut, Lipids, Liver, Liver and urea cycle, Mast cell activation syndrome, Metabolism, Microbiome, Muscles, Oxidative Stress, Pathogens, Sex hormones

This amazing study shows why so many systems in ME/CFS patient's bodies fold under stress.

The Best of Times, The Worst of Times: Ian Lipkin Talks on ME/CFS

by Cort Johnson | Jul 6, 2025 | B-cells, Epstein-Barr Virus, Genetics, Gulf War Illness, Gut, Homepage, Immune, ME/CFS, Metabolism, Pathogens, Research

The famous virus hunter Ian Lipkin is very excited about progress in the ME/CFS field. Funding for his NIH-funded ME/CFS research center at Columbia University, however, has been frozen by the Trump administration.

Hitting the Target? ME/CFS and long COVID T-Cell Researchers on Uncovering the Precise Drivers of the Illnesses

Takeaways From the Big Long COVID Clinical Trials

Are All Roads Leading to the Immune System and the Blood in ME/CFS?

The GLP-1 Agonist Boom in ME/CFS, FM and Long COVID: Insights, Using it, Trials Underway

Gut Reactions: BioMapAI Points to Multiple Dysregulated Systems in ME/CFS

“Screaming Immune Activation”: Major Lipkin Study Finds ME/CFS Systems Folding Under the Stress

The Best of Times, The Worst of Times: Ian Lipkin Talks on ME/CFS

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